R-454B vs R-32

Both are lower-flammability (A2L) refrigerants for new AC and heat pumps; R-454B is a blend with a GWP of 465 that runs close to R-410A, while R-32 is a single component with a GWP of 675 that runs higher: 121.0 psig vs 107.0 psig (dew) at 40°F.

Side by side

Properties
R-454BR-32
Safety groupA2LA2L
GWP (AR4)465675
CompositionR-32 / R-1234yf, 68.9 / 31.1 % by weightDifluoromethane (CH2F2), 100 %
LubricantPOEPOE
Critical temperature173.5°F172.6°F
Saturation pressure (blends: liquid / vapor)
°FR-454B psigR-32 psig
-2024.3 / 22.626.8
045.3 / 42.749.3
2074.0 / 70.380.0
40112.1 / 107.0121.0
60161.3 / 154.6174.1
80223.5 / 215.0241.5
100300.8 / 290.4325.7
120395.6 / 383.5429.3

Computed with CoolProp; gauge pressure at sea level. Full charts: R-454B, R-32.

At a glance

R-454BR-32
MakeupBlend: R-32 / R-1234yf, 68.9 / 31.1 by weightSingle component (difluoromethane)
ASHRAE 34 safety classA2LA2L
GWP, 100-year (EPA Technology Transitions table)465675
Glide at a 40°F dew point2.4°FNone
Critical temperature173.5°F172.6°F
LubricantPOEPOE or PVE formulated for R-32
Charging, per ArkemaAs liquidAs vapor or liquid
EPA SNAP listing, home and light-commercial ACAcceptable subject to use conditions, new equipmentAcceptable subject to use conditions, new equipment

Both are below the 700 GWP limit in EPA's Technology Transitions rule for new residential and light-commercial AC and heat pump systems; R-410A, at 2,088, is not. Carrier (as Puron Advance) and Lennox sell R-454B residential equipment, and Daikin, which builds R-32 equipment under the Daikin, Goodman and Amana brands, compares its R-32 heat pump with R-454B models from Carrier, Lennox, Trane and Rheem.

Operating pressures

Arkema sums it up: R-454B "was designed to closely match the pressure-temperature profile of R-410A", while R-32 "runs at higher pressures than R-410A". At a 40°F evaporator, R-454B reads 107.0 psig (dew point) and R-32 reads 121.0 psig. At a 110°F condensing temperature, R-454B reads 345.9 psig (bubble point) and R-32 reads 374.9 psig.

Those gaps are big enough to matter on a superheat check. An R-32 suction reading of 121.0 psig is a 40°F evaporator, but on an R-454B chart that pressure would read as a dew point of 46.4°F. Set the manifold to the refrigerant on the rating plate.

Glide and charging

R-454B is a near-azeotropic blend with a small glide, so its PT chart lists bubble and dew points; use dew for superheat and bubble for subcooling. R-32 is one compound with a single saturation temperature, so its chart has one column.

That difference shows up in charging. Arkema advises charging R-454B as liquid because it is a blend, while R-32 can go in as vapor or liquid. Daikin says an R-32 system can be topped off in either phase without any change in composition, and that topping off blends is generally not recommended. Chemours, which makes R-454B, says its glide is low enough that it can be topped off after leaks. Follow the equipment manufacturer's service instructions.

Efficiency and charge size claims

Arkema credits R-32 with higher efficiency, better cooling capacity and a smaller refrigerant charge, and credits R-454B with an easier transition from R-410A designs. Daikin's brochure lists a factory charge of 82.6 oz for one of its 3-ton R-32 heat pumps against 90 to 121.6 oz for four competitors' R-454B models. These are manufacturer comparisons of specific products; real differences depend on the equipment.

Safety and equipment

Arkema notes that both are A2L under ASHRAE 34, and Copeland describes A2L refrigerants as lower flammability, with a maximum burning velocity under 10 cm/s. EPA's SNAP listings for both require residential and light-commercial equipment to meet UL 60335-2-40, 3rd edition, and both use A2L cylinders with a red band and left-hand valve threads. AHRI's A2L best practices call for an A2L-rated vacuum pump and recovery tools rated for A2L refrigerants, and AHRI's task force adds leak detectors rated for A2L refrigerants. See A2L refrigerants.

Parts and oil

Components are matched to one refrigerant. Payne's installation instructions for an R-454B heat pump open with "For use with R-454B indoor units only." Daikin says its R-32 systems use POE or PVE oils formulated for R-32, while Honeywell's data sheet recommends POE for R-454B. Copeland notes that A2L refrigerants are only for use in compressors approved for them. AHRI's A2L best practices say to use only OEM-approved replacement parts, so order parts by the model number on the rating plate.

Not interchangeable

Neither refrigerant is a retrofit for R-410A systems, per Arkema and EPA's new-equipment-only listings, and they are not interchangeable with each other. Daikin's pressure-temperature chart notes say A2L refrigerants cannot be used to retrofit a different refrigerant into an existing system and to always use the refrigerant marked on the nameplate. Pressures, glide and oil differ between the two, as the sections above show.

Last reviewed October 10, 2026.

Sources

  1. Arkema, Forane tech tip: R-32 vs R-454B
  2. Chemours, Opteon XL41 (R-454B) Product Information
  3. Daikin, R-32 Refrigerant: Get the Facts (CB-R32-GETFACTS, 06-25)
  4. Daikin, About HFC-32 refrigerant
  5. Carrier, R-454B refrigerant
  6. Lennox, SL25KCV Installation Instructions (508447-01, R-454B)
  7. Payne, PH5SAN5 R-454B Heat Pump Installation Instructions
  8. Honeywell, Solstice 454B Technical Data Sheet
  9. Copeland, AE 93-11 Refrigerant and lubricant approvals
  10. EPA, SNAP substitutes in residential and light commercial air conditioning and heat pumps
  11. Federal Register, SNAP Rule 23 (86 FR 24444, May 6, 2021)
  12. EPA, Technology Transitions HFC restrictions by sector
  13. AHRI, Guideline N-2017, Assignment of Refrigerant Container Colors
  14. Arkema, Forane tech tip: the difference between A2L and A1 cylinders
  15. AHRI, A2L Refrigerants Best Practices
  16. AHRI Safe Refrigerant Transition Task Force, Chapter 2: properties of A2L refrigerants (A2L-rated tools)
  17. EPA, Technology Transitions GWP reference table
  18. Bell, Wronski, Quoilin, Lemort: Pure and Pseudo-pure Fluid Thermophysical Property Evaluation and the Open-Source Thermophysical Property Library CoolProp (Ind. Eng. Chem. Res., 2014)