R-22 replacements

The common R-22 retrofit refrigerants are R-407C (needs POE oil), R-422B (usually keeps the existing oil) and R-427A (POE recommended, usually one oil change); the other route is a new system, which now usually means an A2L system such as R-454B or R-32, or an R-410A system built entirely from components made or imported before 2025.

Side by side

Properties
R-22R-407CR-422BR-427AR-410A
Safety groupA1A1A1A1A1
GWP (AR4)18101774252621382088
CompositionChlorodifluoromethane (CHClF2), 100 %R-32 / R-125 / R-134a, 23 / 25 / 52 % by weightR-125 / R-134a / R-600a, 55 / 42 / 3 % by weightR-32 / R-125 / R-143a / R-134a, 15 / 25 / 10 / 50 % by weightR-32 / R-125, 50 / 50 % by weight
LubricantMineral oil or alkylbenzene (POE also compatible)POEMineral oil, alkylbenzene or POEPOE (tolerates residual mineral oil or alkylbenzene)POE
Critical temperature205.1°F187.0°F179.5°F185.9°F160.4°F
Saturation pressure (blends: liquid / vapor)
°FR-22 psigR-407C psigR-422B psigR-427A psigR-410A psig
-2010.213.7 / 6.510.9 / 5.712.8 / 6.026.3 / 26.2
024.029.5 / 19.424.9 / 18.028.0 / 18.748.4 / 48.2
2043.151.2 / 37.944.2 / 35.548.9 / 36.678.7 / 78.4
4068.680.2 / 63.270.0 / 59.476.8 / 61.2118.8 / 118.4
60101.6118.0 / 96.8103.4 / 90.9113.0 / 93.9170.7 / 170.1
80143.6165.8 / 140.5145.9 / 131.6159.0 / 136.2236.5 / 235.7
100195.9225.5 / 196.1198.9 / 183.1216.2 / 190.0318.5 / 317.6
120260.0298.6 / 265.8263.9 / 247.1286.3 / 257.3419.5 / 418.3

Computed with CoolProp; gauge pressure at sea level. Full charts: R-22, R-407C, R-422B, R-427A, R-410A.

Why R-22 systems need a plan

EPA ended production and import of HCFC-22 on January 1, 2020. After that, only recycled, reclaimed or previously produced R-22 can be used to service existing equipment. EPA rules have also barred selling pre-charged R-22 appliances made on or after January 1, 2010. That leaves three choices for a working R-22 system: keep servicing it with recycled, reclaimed or previously produced R-22, retrofit it to an HFC blend, or replace it. In residential and light-commercial AC, EPA lists R-407C and R-422B as acceptable for retrofit and new equipment, and R-427A for retrofit.

Side by side

R-22R-407CR-422BR-427A
MakeupSingle HCFCR-32 / R-125 / R-134a, 23 / 25 / 52R-125 / R-134a / R-600a, 55 / 42 / 3R-32, R-125, R-143a, R-134a
Safety classA1A1A1A1
GWP (IPCC AR4)1,8101,7742,5252,138
OilMineral or alkylbenzenePOE; residual mineral oil about 5% or lessUsually no change; add POE if oil return is poorPOE recommended; 20% POE or a full change
Dew pressure at 40°F68.6 psig63.2 psig59.4 psig61.2 psig
Bubble pressure at 110°F226.4 psig260.3 psig229.8 psig249.5 psig
Glide near 40°F evaporatingNone11.1°F7.6°F10.5°F
Capacity vs R-22 (maker)98 to 106% in coolingSimilar in most systemsAbout 3% lower at 45°F evaporating
Charge vs original R-2290 to 95% by weightStart near 85%, finish near 95%Start at 90%, as liquid

All three are zeotropic blends with real glide, so read the dew column for superheat and the bubble column for subcooling (why), and charge them as liquid.

R-407C

Chemours' R-407C retrofit guidelines require polyolester (POE) oil, with residual mineral oil around 5% or less of the total, and Chemours' R-407C and R-410A bulletin says three oil changes are generally recommended when converting a system to HFC refrigerants and POE. Copeland's changeover guidelines approve only POE for R-407C and R-427A in its compressors, recommend flushing to no more than 5% residual mineral oil, and say some systems perform adequately with up to 10%. Chemours reports a slightly higher discharge pressure than with R-22. Copeland also notes that with glide blends such as R-407C and R-427A, refrigerant entering the evaporator is about 10°F colder than the vapor leaving it, so low-pressure controls set for R-22 may need new cut-in and cut-out points.

R-422B

Chemours sells R-422B as Freon NU-22B. Its guidelines say it works with traditional and newer lubricants and that in most cases no change of lubricant type is needed. If oil return looks erratic, Chemours advises adding POE at about 20% of the total oil charge, and recommends a one-time POE change for systems with Trane 3-D or Danfoss SM scroll compressors. It reports similar cooling capacity and efficiency to R-22 in most systems, with a lower discharge temperature, and says systems can be topped off without removing the whole charge.

R-427A

Arkema sells R-427A as Forane 427A. Its retrofit guidelines say it is compatible with mineral and alkylbenzene oil but not fully miscible, and recommend converting 20% of the oil to POE or changing over completely; Trane 3-D, Danfoss SM and all screw compressors need a full POE change. Arkema's procedure adds that R-427A tolerates a high residual of the original oil, so one oil change is usually enough. Arkema puts the capacity loss at about 3% at a 45°F evaporator and expects slightly lower suction and slightly higher discharge pressure than R-22.

Replacing the system instead

R-410A is not a retrofit option for R-22 equipment: EPA lists it for new residential AC equipment only. It also runs far higher pressures, 118.8 psig at 40°F against 68.6 psig for R-22, and Chemours notes that HFCs such as R-410A are miscible with POE oil but not with mineral oil. Replacement systems are matched sets; Payne's R-454B heat pump instructions, for example, open with "For use with R-454B indoor units only."

Since January 1, 2025, EPA's Technology Transitions rule has limited new residential and light-commercial AC and heat pump systems to refrigerants under 700 GWP. Under the final rule effective July 27, 2026, a new R-410A system can still be installed only if every specified component was manufactured in or imported into the US before January 1, 2025. Otherwise a replacement uses an A2L refrigerant such as R-454B or R-32. Check the manufacturer's instructions on whether the existing line set can be reused.

Steps the retrofit guides share

  • Recover the full R-22 charge first.
  • Change oil as the guide for that refrigerant and compressor requires.
  • Replace the filter drier.
  • Charge as liquid, start below the original R-22 charge, and finish by superheat or subcooling.
  • Label the system with the refrigerant and oil now in it.

Last reviewed October 10, 2026.

Sources

  1. EPA, Phaseout of Class II ozone-depleting substances (HCFC-22 schedule)
  2. EPA, Purchasing and repairing home air conditioners or heat pumps (R-22 servicing)
  3. EPA, Ozone-depleting substances (HCFC-22 GWP)
  4. eCFR, 40 CFR 82 subpart I (pre-charged HCFC-22 appliances)
  5. EPA, SNAP substitutes in residential and light commercial air conditioning and heat pumps
  6. EPA, Technology Transitions GWP reference table
  7. AHRI Safe Refrigerant Transition Task Force, Chapter 2: properties of A2L refrigerants (ASHRAE 34 class of R-22)
  8. Chemours, Freon 410A and 407C properties, uses, storage and handling (oil changes, POE miscibility)
  9. Payne, PH5SAN5 R-454B Heat Pump Installation Instructions
  10. Chemours, Freon 407C Retrofit Guidelines
  11. Chemours, Freon MO99 and NU-22B Retrofit Guidelines
  12. Chemours, US Refrigerant Replacement Guide (GWP values)
  13. Arkema, Forane Retrofit Guidelines (2022)
  14. Arkema, Forane Recommended Retrofit Procedure (2022)
  15. Arkema, Forane R-22 to 427A Q&A sheet
  16. Arkema, Forane 427A product page (GWP)
  17. Copeland, AE 95-14 Refrigerant Changeover Guidelines
  18. Federal Register, Technology Transitions reconsideration final rule (91 FR 31284, May 26, 2026)
  19. Bell, Wronski, Quoilin, Lemort: Pure and Pseudo-pure Fluid Thermophysical Property Evaluation and the Open-Source Thermophysical Property Library CoolProp (Ind. Eng. Chem. Res., 2014)